How health changes between visits
Relationships between medical events, treatment and everyday observations over time.
Science and research
Longitudinal health analysis — from individuals to populations.
The BIOS research system connects clinical data, observations and device signals over time. Each project operates under its own protocol, consent and access rules.
Results are published only after the methods and limitations have been reviewed.
01
Data over time
ProgrammeChanges, not a single snapshot.
02
Multiple data types
ProtocolDocuments, laboratory data, observations and devices.
03
Reproducibility
FoundationVersions, data provenance and a fixed analysis method.
04
Value for participants
PrincipleConsent, clear participation terms and the right to withdraw.
Research agenda
Six research areas
Each project has a protocol, a clinical partner and an ethics review.
Which longitudinal patterns recur across groups
Sequences of change, common trajectories and differences between predefined cohorts.
How to compare different data types
Lab measurements, documents, symptoms, devices and observations retain their provenance and timescale.
How to account for missing measurements
What missing data means for a result, and which conclusions it cannot support.
How AI helps experts test a hypothesis
Supporting evidence, discrepancies, alternatives and the effect of the interface on professional decisions.
How data between visits changes monitoring
Appointment preparation, sharing results and following an agreed plan.
Infrastructure
From consent to a reproducible result
Only within an approved project.
Participation
Clear terms
Consent version
The right to withdraw
Collection
Medical records
Participant observations
Devices and laboratories
Preparation
A shared model
Data provenance
Quality flags
Analysis
A fixed sample
Algorithm version
Repeatable analysis
Result
Overall findings
Publication
Feedback to participants
Partnerships
Four ways for research centres to participate
Validate BIOS modules or conduct a joint study.
Evaluate a BIOS component
Extraction, normalisation, hypotheses or the interface.
Design a study
BIOS provides the technology; the partner contributes scientific expertise.
Use BIOS modules
Consent, data collection, provenance and versioning.
Develop shared approaches
Data models, benchmarks and uncertainty assessment.
Scientific principles
Protocol, ethics and reproducibility
Protocol before results
Objectives, outcomes, sample and criteria are defined before analysis where the study design allows.
Ethics before access
Scientific value alone does not override consent, data minimisation or independent risk assessment.
Versions alongside findings
Data, code, models and the knowledge base are versioned so the result can be reproduced.
Limitations alongside results
Sampling bias, missing data, conflicts of interest and negative results are not omitted from public descriptions.
Feedback for participants
Where feasible and safe, participants receive clear information about the aims and aggregate results of the study.
Status
What is available now
July 2026.
Protocol discussions
Joint definition of the research question and data requirements.
Evaluation criteria
Technical and analytical requirements for BIOS components.
Research data flow
Starts after legal, ethical and technical review.
Open datasets and publications
Will be released only after results are verified and publication is authorised.
Propose a question for a joint study.
To start, share the objective, study design and intended role of BIOS.